JP83
货号：
10008660-5mg 基本售价：
420.0 元 规格：
5 mg
产品信息
概述| 货号 | 10008660-5mg |
| 描述 | The enzyme fatty acyl amide hydrolase (FAAH) is widely expressed in brain and other tissues, and is capable of hydrolyzing anandamide (AEA) and other simple esters and amides with long unsaturated acyl chains.1 JP83 is an irreversible fatty acyl amide hydrolase (FAAH) inhibitor of the carbamate class with an IC50 of 14 nM for the human recombinant enzyme when tested using radiolabeled oleamide as the substrate.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Zhang, Y.H.,Zhang, G.Y.,Mollat, P., et al. Purification, characterization, and cellular localization of the 100-kDa human placental GTPase-activating protein. The Journal of Biological Chemisty 268, 18875-18881 (1993).
2.Alexander, J.P., and Cravatt, B.F. Mechanism of carbmate inactivation of FAAH: Implications for the design of covalent inhibitors and in vivo functional probes for enzymes. Chemistry & Biology 12, 1179-1187 (2005).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 416.5 |
| 分子式 | C26H28N2O3 |
| CAS号 | 887264-44-0 |
| 稳定性 | ≥ 2 years |
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