Estrone-d2
货号：
9002844-500ug 基本售价：
406.0 元 规格：
500 ug
产品信息
概述| 货号 | 9002844-500ug |
| 描述 | Estrone-d2 is intended for use as an internal standard for the quantification of estrone (Item Nos. ISO60165|10006485) by GC- or LC-MS. Estrone is one of the three naturally occurring estrogens, the others being estradiol (Item Nos. ISO60155|10006315) and estriol (Item Nos. ISO60164|10006484).1 Estrone is synthesized from androstenedione (Item No. ISO60161) by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver.1,2 Serum concentrations of estrone in premenopausal women fluctuate according to the menstrual cycle and becomes the most predominant estrogen in postmenopausal women.1 The binding affinities of estrone to the estrogen receptors α and β are approximately 60% and 37% relative to estradiol.1 |
| 别名 | E1-d2; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Gruber, C.J.,Tschugguel, W.,Schneeberger, C., et al. Production and actions of estrogens. New England Journal of Medicine 346(5), 340-352 (2002).
2.Vance, D.E. Cholesterol and related derivatives. Biochemistry 2nd ed., 725-748 (1988).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 272.4 |
| 分子式 | C18H20D2O2 |
| CAS号 | 350820-16-5 |
| 稳定性 | ≥ 2 years |
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