货号 | 70935-50mg |
描述 | Phenolic compounds, particularly flavonoids, from plant sources have long been observed to have antioxidant activity with potential benefits for human health.1,2,3 (−)-Epigallocatechin gallate (EGCG) is a principle phenolic antioxidant found in a variety of plants, including green and black tea. EGCG inhibits cellular oxidation of low-density lipoproteins.4 EGCG is readily detected in human and rat plasma at ng/ml levels following oral ingestion.5 ECGC inhibits the peroxynitrite-induced formation of the oxidative injury markers 8-hydroxy-2-deoxy guanosine and 3-nitrotyrosine.6 |
别名 | EGCG;NVP-XAA723;Tea catechin;Teavigo; |
供应商 | Cayman |
应用文献 | |
1.Frémont, L.,Belguendouz, L. and Delpal, S. Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids. Life Sciences 64, 2511-2521 (1999). 2.Johnson, J.L. and Maddipati, K.R. Paradoxical effects of resveratrol on the two prostaglandin H synthases. Prostaglandins & Other Lipid Mediators 56, 131-143 (1998). 3.Miller, N.J. and Rice-Evans, C. Antioxidant activity of resveratrol in red wine. Clinical Chemistry 41, 1789-1789 (1995). 4.Yoshida, H.,Ishikawa, T.,Hosoai, H., et al. Inhibitory effect of tea flavonoids on the ability of cells to oxidize low density lipoprotein. Biochemical Pharmacology 58, 1695-1703 (1999). 5.Nakagawa, K. and Miyazawa, T. Chemiluminescence - high-performance liquid chromatographic determination of tea catechin, (−)-epigallacatechin 3-gallate, at picomole levels in rat and human plasma. Analytical Biochemistry 248, 41-49 (1997). 6.Fiala, E.S.,Sodum, R.S.,Bhattacharya, M., et al. (−)-Epigallacatechin gallate, a polyphenolic tea antioxidant, inhibits peroxynitrite-mediated formation of 8-oxodeoxyguanosine and 3-nitrotyrosine. Experientia 52, 922-926 (1996). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 458.4 |
分子式 | C22H18O11 |
CAS号 | 989-51-5 |
稳定性 | ≥ 2 years |
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