Tetramethylrhodamine ethyl ester (perchlorate)
货号：
21426-5mg 基本售价：
406.0 元 规格：
5 mg
产品信息
概述| 货号 | 21426-5mg |
| 描述 | Tetramethylrhodamine ethyl ester (TMRE) (perchlorate) is a non-cytotoxic cell-permeant fluorogenic dye most commonly used to assess mitochondrial function using live cell fluorescence microscopy and flow cytometry.1,2 It displays excitation/emission spectra of 550/575 nm, respectively. Due to the polarization of the mitochondrial membrane, TMRE is taken up into healthy mitochondria. However, when the membrane is depolarized, as in apoptosis, it is not taken up or is released from the mitochondria. Thus, the strength of the fluorescence signal in mitochondria is used to assess cell viability. |
| 别名 | TMRE;TMR ethyl ester; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Farkas, D.L.,Wei, M.-d.,Febbroriello, P., et al. Simultaneous imaging of cell and mitochondrial membrane potentials. Biophys J. 56(6), 1053-1069 (1989).
2.Sunaga, D.,Tanno, M.,Kuno, A., et al. Accelerated recovery of mitochondrial membrane potential by GSK-3β inactivation affords cardiomyocytes protection from oxidant-induced necrosis. PLoS One 9(11), e112529 (2014).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 515 |
| 分子式 | C26H27N2O3 • ClO4 |
| CAS号 | 115532-52-0 |
| 稳定性 | ≥ 2 years |
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