CK-1827452
货号：
21074-1mg 基本售价：
406.0 元 规格：
1 mg
产品信息
概述| 货号 | 21074-1mg |
| 描述 | CK-1827452 is a diaryl urea compound that increases cardiac myosin ATPase activity in a dose-dependent manner that is selective for cardiac myosin over non-cardiac myosins.1 It promotes myosin cross-bridge formation, increasing the duration and amount of myocyte contraction without affecting intracellular calcium or cAMP.1 It has been shown to increase cardiac efficiency in clinical studies of patients with chronic heart failure.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Teerlink, J.R. A novel approach to improve cardiac performance: Cardiac myosin activators. Heart Fail Rev. 14(4), 289-298 (2009).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 401.4 |
| 分子式 | C20H24FN5O3 |
| CAS号 | 873697-71-3 |
| 稳定性 | ≥ 2 years |
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