| 货号 | 21050-25mg |
| 描述 | 6,7-dimethyl-5,6,7,8-Tetrahydropterin is a synthetic analog of tetrahydro-L-biopterin (BH4; Item No. 81880), a required cofactor for all NOS isoforms, phenylalanine, tyrosine, and tryptophan hydroxylases, and other enzymes.1,2,3,4,5 |
| 别名 | DMPH4;NSC 87950; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Mayer, B. and Werner, E.R. In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide. Naunyn-Schmiedebergs Archives of Pharmacology 351, 453-463 (1995). 2.Chaube, R. and Joy, K.P. Effects of ovariectomy and oestradiol-17beta replacement on brain tyrosine hydroxylase in the catfish Heteropneustes fossilis: changes in in vivo activity and kinetic parameters. J. Endocrinol. 175(2), 329-342 (2002). 3.Jennings, I. and Cotton, R. Structural similarities among enzyme pterin binding sites as demonstrated by a monoclonal anti-idiotypic antibody. J. Biol. Chem. 265(4), 1885-1889 (1990). 4.Suckling, C.J.,Gibson, C.L.,Huggan, J.K., et al. 6-Acetyl-7,7-dimethyl-5,6,7,8-tetrahydropterin is an activator of nitric oxide synthases. Bioorg. Med. Chem. Lett. 5(1), 1563-1566 (2008). 5.Volner, A.,Zoidakis, J. and Abu-Omar, M.M. Order of substrate binding in bacterial phenylalanine hydroxylase and its mechanistic implication for pterin-dependent oxygenases. J. Biol. Inorg. Chem. 8(1-2), 121-128 (2002). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 231.7 |
| 分子式 | C8H13N5O • HCl |
| CAS号 | 945-43-7 |
| 稳定性 | ≥ 2 years |
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