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货号： bs-1860R 基本售价： 780.0 元 规格： 50ul
- 规格：50ul
- 价格：780.00元
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-1860R
- 英文名称
- CALCRL
- 中文名称
- 降钙素基因相关肽1型受体抗体
- 别 名
- CGRPR; CRLR; calcitonin receptor like precursor; Calcitonin gene related peptide type 1 receptor; Calcitonin receptor like; CGRP type 1 receptor; Calcitonin gene related peptide type 1 receptor; Calcitonin receptor like; Calcitonin Receptor Like Receptor; CGRP type 1 receptor; CALRL_HUMAN.
- Specific References (1) | bs-1860R has been referenced in 1 publications.[IF=4.60] Toriyama, Yuichi, et al. "Pathophysiological Function of Endogenous Calcitonin Gene–Related Peptide in Ocular Vascular Diseases." The American Journal of Pathology (2015). Mouse.PubMed:25857228
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 细胞生物 免疫学 神经生物学 信号转导 G蛋白偶联受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 50kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CGRPR1:281-380/461 <Cytoplasmic>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
CRLR is a receptor for calcitonin gene related peptide type 1. The activity of CRLR is mediated by G proteins which activate adenylyl cyclase. CRLR expression has been reported in brain, lung, blood vessel, liver, and intestinal tract. ESTs have been isolated from B Cell/lung/testis, bone marrow, embryo, lung, and synovium libraries.
Function:
Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Subunit:
Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Tissue Specificity:
Predominantly expressed in the lung and heart.
Similarity:
Belongs to the G-protein coupled receptor 2 family.
SWISS:
Q16602
Gene ID:
10203
Database links:Entrez Gene: 10203 Human
Entrez Gene: 54598 Mouse
Entrez Gene: 397172 Pig
Entrez Gene: 25029 Rat
Entrez Gene: 527140 Cow
Omim: 114190 Human
SwissProt: Q16602 Human
SwissProt: Q9R1W5 Mouse
SwissProt: Q8WN93 Pig
SwissProt: Q63118 Rat
Unigene: 470882 Human
Unigene: 11202 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Sample:
Lung (Mouse) Lysate at 30 ug
Lymph(Mouse) Lysate at 30 ug
Primary: Anti- CRLR (bs-1860R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 50 kD
Observed band size: 50 kD