(−)-Nicotine (tartrate)
货号:
20887-500mg 基本售价:
406.0 元 规格:
500 mg
产品信息
概述货号 | 20887-500mg |
描述 | (−)-Nicotine is the dominant form of the natural alkaloid nicotine.1 It acts as an agonist of neuronal nicotinic acetylcholine receptors (nAChRs) and possesses addictive and teratogenic properties.2 (−)-(S)-Nicotine is significantly more active at binding nAChRs compared to the (+)-(R) antipode, thus nicotine is typically synthesized as (−)-(S)-nicotine with only 0.2-1% of the (+)-(R) isomer present.1 |
别名 | NSC 97238; |
是否危险品 | 是 |
性能供应商 | Cayman |
应用文献 |
1.Clayton, P.,Lu, A. and Bishop, L. The pyrolysis of (−)-(S)-nicotine: Racemization and decomposition. Chirality 22(4), 442-446 (2010). 2.Zaveri, N.,Jiang, F.,Olsen, C., et al. Novel α3β4 nicotinic acetylcholine receptor-selective ligands. Discovery, structure-activity studies, and pharmacological evaluation. Journal of Medicinal Chemistry 53, 8187-8191 (2010).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 462.4 |
分子式 | C10H14N2 • 2C4H6O6 |
CAS号 | 65-31-6 |
稳定性 | ≥ 2 years |
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