AZD 5153
货号：
20864-1mg 基本售价：
406.0 元 规格：
1 mg
产品信息
概述| 货号 | 20864-1mg |
| 描述 | AZD 5153 an orally available, bivalent inhibitor of the bromodomain and extraterminal (BET) protein BRD4 (IC50 = 5 nM).1 It can simultaneously bind two bromodomains in BRD4, which has been shown to increase antitumor activity in multiple xenograft models of acute myeloid leukemia, multiple myeloma, and diffuse large B cell lymphoma.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Rhyasen, G.W.,Hattersley, M.M.,Yao, Y., et al. AZD5153: A novel bivalent BET bromodomain inhibitor highly active against hematologic malignancies. Mol. Cancer Ther. 15(11), 2563-2574 (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 479.6 |
| 分子式 | C25H33N7O3 |
| CAS号 | 1869912-39-9 |
| 稳定性 | ≥ 2 years |
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