HX 531
货号:
20762-1mg 基本售价:
406.0 元 规格:
1 mg
产品信息
概述货号 | 20762-1mg |
描述 | HX 531 is an antagonist of the retinoid X receptor (RXR) with an IC50 value of 18 nM that inhibits 9-cis retinoic acid (Item No. 14587)-induced transactivation of RXR.1 It has been shown to reduce triglyceride content in white adipose tissue, skeletal muscle, and the liver of mice on a high fat diet.2 |
性能供应商 | Cayman |
应用文献 |
1.Konta, T.,Xu, Q.,Furusu, A., et al. Selective roles of retinoic acid receptor and retinoid x receptor in the suppression of apoptosis by all-trans-retinoic acid. J. Biol. Chem. 276(16), 12697-12701 (2001). 2.Yamauchi, T.,Waki, H.,Kamon, J., et al. Inhibition of RXR and PPARγ ameliorates diet-induced obesity and type 2 diabetes. J. Clin. Invest. 108(7), 1001-1013 (2001).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 483.6 |
分子式 | C29H29N3O4 |
CAS号 | 188844-34-0 |
稳定性 | ≥ 2 years |
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