BI-7273
货号：
20311-1mg 基本售价：
406.0 元 规格：
1 mg
产品信息
概述| 货号 | 20311-1mg |
| 描述 | BI-7273 is a potent BRD9 bromodomain inhibitor (Kd = 15.4 nM; IC50 = 19 nM) that less effectively inhibits the functionally and structurally related BRD7 bromodomain (IC50 = 117 nM).1 It is without effect against the bromodomains of BRD2 and BRD4, as well as a panel of kinases. BI-7273 inhibits the growth of EOL-1 acute myeloid leukemia cells in vitro(EC50 = 1.4 µM).1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Martin, L.J.,Koegl, M.,Bader, G., et al. Structure-based design of an in vivo active selective BRD9 inhibitor. Journal of Medicinal Chemistry 59(10), 4462-4475 (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 353.4 |
| 分子式 | C20H23N3O3 |
| CAS号 | 1883429-21-7 |
| 稳定性 | ≥ 2 years |
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