AZ 6102
货号：
19898-1mg 基本售价：
406.0 元 规格：
1 mg
产品信息
概述| 货号 | 19898-1mg |
| 描述 | AZ 6102 is an inhibitor of tankyrases (TNKS) 1 and 2 with IC50 values of 3 and 1 nM, respectively.1 It demonstrates 100-fold selectivity for TNKS1/2 over PARP1, PARP2, and PARP6 (IC50s = 2, 0.5, and >3 µM, respectively).1 By inhibiting TNKS1/2, AZ6120 has been shown to inhibit Wnt signaling in DLD-1 cells with an IC50 value of 5 nM.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Johannes, J.W.,Almeida, L.,Barlaam, B., et al. Pyrimidinone nicotinamide mimetics as selective tankyrase and Wnt pathways inhibitors suitable for in vivo pharmacology. ACS Med. Chem. Lett. 6, 254-259 (2015).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 428.5 |
| 分子式 | C25H28N6O |
| CAS号 | 1645286-75-4 |
| 稳定性 | ≥ 2 years |
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