β-Elemene
货号：
19641-10mg 基本售价：
406.0 元 规格：
10 mg
产品信息
概述| 货号 | 19641-10mg |
| 描述 | β-Elemene is a natural sesquiterpene found in various plants and imparts floral aromas to some plants. This compound has been reported to inhibit the proliferation of a wide range of tumors.1 In HepG2 cells, 10-40 µg/ml β-elemene can dose-dependently induce apoptosis and cell cycle arrest in the G2/M phase, upregulating Fas/FasL expression.2 It has been shown to enhance the sensitivity of Hep3B, Hu7, MHCC97H, and MHCCLM3 cells to oxaliplatin (Item No. 13106; IC50s = 1.79, 3.27, 2.54, and 5.73 µM, respectively) by upregulating copper transporter 1, a major regulator of intracellular platinum accumulation.3 |
| 别名 | (-)-β-Elemene;Levo-β-elemene; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Chen, M.,Zhang, J.,Yu, S., et al. Anti-lung-cancer activity and liposome-based delivery systems of β-elemene. Evidence-Based Complementary and alternative Medicine 2012:259523, (2012).
2.Dai, Z.J.,Tang, W.,Lu, W.F., et al. Antiproliferative and apoptotic effects of β-elemene on human hepatoma HepG2 cells. Cancer Cell Int. 13(1), (2013).
3.Li, X.,Lin, Z.,Zhang, B., et al. β-elemene sensitizes hepatocellular carcinoma cells to oxaliplatin by preventing oxaliplatin-induced degradation of copper transporter 1. Sci.Rep. 6:21010, (2016).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 204.4 |
| 分子式 | C15H24 |
| CAS号 | 515-13-9 |
| 稳定性 | ≥ 1 year |
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