Mps1-IN-1
货号：
19175-500ug 基本售价：
406.0 元 规格：
500 ug
产品信息
概述| 货号 | 19175-500ug |
| 描述 | Mps1-IN-1 is a selective inhibitor of monopolar spindle 1 (Mps1) kinase (IC50 = 367 nM), a dual-specificity kinase involved in spindle assembly checkpoint and the maintenance of chromosomal stability.1 It exhibits greater than 1,000-fold selectivity against a panel of 352 kinases.1 Mps1-IN-1 has been shown to disrupt the recruitment of Mad2 to kinetochores and to increase the frequency of multipolar mitosis in U2OS cells.1 |
| 别名 | Monopolar Spindle 1 Kinase Inhibitor 1;Mps1 Kinase Inhibitor 1; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kwiatkowski, N.,Jelluma, N.,Filippakopoulos, P., et al. Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function. Nat.Chem.Biol. 6(5), 359-368 (2010).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 535.7 |
| 分子式 | C28H33N5O4S |
| CAS号 | 1125593-20-5 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
