GSK621
货号：
19155-500ug 基本售价：
406.0 元 规格：
500 ug
产品信息
概述| 货号 | 19155-500ug |
| 描述 | GSK621 is an activator of AMP-activated protein kinase (AMPK). It has been shown to increase phosphorylation at AMPKα T172, a marker of AMPK activation, in both acute myeloid leukemia (AML) cell lines and primary AML samples.1 GSK621 is reported to reduce the proliferation of AML cell lines (IC50s = 13-30 μM), triggering autophagy via the eIF2α/ATF4 signaling pathway.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sujobert, P.,Poulain, L.,Paubelle, E., et al. Co-activation of AMPK and mTORC1 induces cytotoxicity in acute myeloid leukemia. Cell Rep. 11(9), 1446-1457 (2015).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 489.9 |
| 分子式 | C26H20ClN3O5 |
| CAS号 | 1346607-05-3 |
| 稳定性 | ≥ 2 years |
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