| 货号 | 18890-10mg |
| 描述 | D-Mannose-6-phosphate (M6P) is a phosphorylated aldohexose that has diverse physiological roles. It can be used to produce glucose as an energy source, converted to mannitol to serve as an osmolyte or metabolic store, or directed to the N-glycosylation pathway.1,2 M6P is also a ligand for both cation-dependent and -independent receptors and binds, as part of an N-glycan, to mannose receptor homology domains on other proteins.3,4,5,6 |
| 别名 | M6P; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Sharma, V.,Ichikawa, M. and Freeze, H.H. Mannose metabolism: More than meets the eye. Biochemical and Biophysical Research Communications 453(2), 220-228 (2014). 2.Meena, M.,Prasad, V.,Zehra, A., et al. Mannitol metabolism during pathogenic fungal-host interactions under stressed conditions. Front.Microbiol. 6, (2015). 3.Ferlinz, K.,Kopal, G.,Bernardo, K., et al. Human acid ceramidase. Processing, glycosylation, and lysosomal targeting. The Journal of Biological Chemisty 276 (38), 35352-35360 (2001). 4.Saris, J.J.,Derkx, F.H.M.,De Bruin, R.J.A., et al. High-affinity prorenin binding to cardiac man-6-P/IGF-II receptors precedes proteolytic activation to renin. American Journal of Physiology.Heart and Circulatory Physiology 280, H1706-H1715 (2001). 5.DAlessio, C. and Dahms, N.M. Glucosidase II and MRH-domain containing proteins in the secretory pathway. Curr.Protein Pept.Sci. 16(1), 31-48 (2015). 6.Hosokawa, N.,Kamiya, Y. and Kato, K. The role of MRH domain-containing lectins in ERAD. Glycobiology 20(6), 651-660 (2010). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 304.1 |
| 分子式 | C6H11O9P • 2Na [XH2O] |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |