S3QEL-2
货号：
18556-5mg 基本售价：
406.0 元 规格：
5 mg
产品信息
概述| 货号 | 18556-5mg |
| 描述 | S3QEL-2 is a cell-permeable, selective suppressor of electron leak from mitochondrial respiratory complex III, inhibiting site IIIQo superoxide production (IC50 = 1.7 µM) without altering normal bioenergetics function.1 It reduces production of H2O2 during oxidation of glutamate plus malate to 25% of the control level. S3QEL-2 also protects against ROS-induced cell stress in pancreatic β-cells and decreases HIF-1α induction in response to hypoxia. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Orr, A.L.,Vargas, L.,Turk, C.N., et al. Suppressors of superoxide production from mitochondrial complex III. Nat. Chem. Biol. 11, 834-840 (2015).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 323.4 |
| 分子式 | C19H25N5 |
| CAS号 | 890888-12-7 |
| 稳定性 | ≥ 2 years |
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