| 货号 | 18506-1mg |
| 描述 | Aminopeptidase B is a Zn2+-dependent exopeptidase that selectively removes arginine and/or lysine from the amino terminus of peptide substrates.1 This enzyme is a metalloprotease commonly found on the surface of mammalian cells, including macrophages and lymphocytes. Arphamenine B is an aminopeptidase B inhibitor first isolated from bacteria.2,3 Like the aminopeptidase inhibitors bestatin (Item No. 70520) and amastatin (Item No. 16719), arphamenine B enhances immune responses.2 Arphamenine B is commonly used to characterize novel proteases.4,5 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Foulon, T.,Cadel, S. and Cohen, P. Aminopeptidase B (EC 3.4.11.6). International Journal of Biochemistry and Cell Biology 31(7), 747-750 (1999). 2.Umezawa, H.,Aoyagi, T.,Ohuchi, S., et al. Arphamenines A and B, new inhibitors of aminopeptidase B, produced by bacteria. J.Antibiot.(Tokyo) 36(11), 1572-1575 (1983). 3.Ohuchi, S.,Suda, H.,Naganawa, H., et al. The structure of arphamenines A and B. J.Antibiot.(Tokyo) 36(11), 1576-1580 (1983). 4.Keane, F. and OCuinn, G. Two broad-specificity dipeptide hydrolysing activities from cytoplasm of guinea pig brain, both of which contain prolinase but neither of which contain carnosinase activity. Neuroscience Research 44(1), 111-120 (2002). 5.Kubo, H.,Kotani, M.,Yamamaoto, Y., et al. Involvement of sperm proteases in the binding of sperm to the vitelline envelope in Xenopus laevis. Zoolog.Sci. 25(1), 80-87 (2008). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 385.4 |
| 分子式 | C16H24N4O4 • 1/2H2SO4 |
| CAS号 | 144110-38-3 |
| 稳定性 | ≥ 2 years |
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