GSK2269557
货号：
17388-1mg 基本售价：
406.0 元 规格：
1 mg
产品信息
概述| 货号 | 17388-1mg |
| 描述 | GSK2269557 is an inhibitor of PI3Kδ (pKi = 9.9) that is >1,000-fold selective for PI3Kδ over PI3Kα, β, and γ isoforms.1 It is reported to be active in a brown Norway rat acute ovalbumin-induced allergic asthma model of Th2-driven lung inflammation (ED50 = 67 µg/kg).1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Down, K.,Amour, A.,Baldwin, I.R., et al. Optimization of novel indazoles as highly potent and selective inhibitors of phosphoinositide 3-kinase δ for the treatment of respiratory disease. J. Med. Chem. 58(18), 7381-7399 (2015).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 477 |
| 分子式 | C26H28N6O • HCl |
| CAS号 | 1254036-77-5 |
| 稳定性 | ≥ 2 years |
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