Rebamipide
货号：
17186-500mg 基本售价：
406.0 元 规格：
500 mg
产品信息
概述| 货号 | 17186-500mg |
| 描述 | Rebamipide is a quinolinone derivative that stimulates endogenous PGE2 generation in gastric mucosa, enhancing gastric mucosal defense in a COX-2-dependent manner.1 Rebamipide has been shown to inhibit the production of reactive oxygen species and to decrease cytokine release induced by H. pyloriinfection.1 A daily oral dose of 100 mg/kg was found to be protective against the development of pyloric channel ulcers in Mongolian gerbils infected with H. pylori.1 In addition to the stomach, rebamipide can also enhance secretion of mucin covering the conjunctiva and cornea, which is important for tear film adhesion.2 |
| 别名 | OPC 12759; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Genta, R.M. Review article: The role of rebamipide in the management of inflammatory disease of the gastrointestinal tract. Alimentary Pharmacology and Therapeutics 18(Suppl 1), 8-13 (2003).
2.Kashima, T.,Itakura, H.,Akiyama, H., et al. Rebamipide ophthalmic suspension for the treatment of dry eye syndrome: A critical appraisal. Clin.Ophthalmol. 8, 1003-1010 (2014).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 370.8 |
| 分子式 | C19H15ClN2O4 |
| CAS号 | 90098-04-7 |
| 稳定性 | ≥ 2 years |
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