UK 5099
货号：
16980-1mg 基本售价：
406.0 元 规格：
1 mg
产品信息
概述| 货号 | 16980-1mg |
| 描述 | Pyruvate transport into mitochondria is facilitated by mitochondrial pyruvate carrier (MPC) 1 and 2, two small transmembrane proteins that are part of a larger 150 kDa protein transport complex in the inner mitochondrial membrane.1,2 UK 5099 is a specific and potent inhibitor of MPC carrier activity.3,4 It potently inhibits pyruvate-dependent oxygen consumption by rat heart mitochondria with an IC50 value of 50 nM.3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Herzig, S.,Raemy, E.,Montessuit, S., et al. Identification and functional expression of the mitochondrial pyruvate carrier. Science 337, 93-96 (2012).
2.Halestrap, A.P. The mitochondrial pyruvate carrier: Kinetics and specificity for substrates and inhibitors. Biochemistry Journal 148, 85-96 (1975).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 288.3 |
| 分子式 | C18H12N2O2 |
| CAS号 | 56396-35-1 |
| 稳定性 | ≥ 2 years |
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