| 货号 | 16468-10mg |
| 描述 | Rifamycins are antibiotics that inhibit DNA-dependent RNA polymerases and are usually bactericidal against Gram-positive bacteria but bacteriostatic against Gram-negative bacteria.1 Rifamycins are also effective against Mycobacterium species, including M. tuberculosis.1 Rifabutin is a broad-spectrum rifamycin antibiotic that has applications against tuberculosis, H. pylori,M. aviumcomplex,Chlamydia, and other bacteria.2,3,4 It is also useful in co-infections with human immunodeficiency virus, including tuberculosis.5,6 |
| 别名 | Ansamycin;LM-427; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Kohanski, M.A.,Dwyer, D.J. and Collins, J.J. How antibiotics kill bacteria: From targets to networks. Nat. Rev. Microbiol. 8(6), 423-435 (2010). 2.Horne, D.J.,Spitters, C. and Narita, M. Experience with rifabutin replacing rifampin in the treatment of tuberculosis. Int.J.Tuberc.Lung Dis. 15(11), 1485-1489 (2011). 3.Song, M. and Ang, T.L. Second and third line treatment options for Helicobacter pylori eradication. World Journal of Gastroenterology 20(6), 1517-1528 (2014). 4.Kunin, C.M. Antimicrobial activity of rifabutin. Clinical Infectious Diseases 22, S3-S14 (1996). 5.Khan, F.A.,Minion, J.,Pai, M., et al. Treatment of active tuberculosis in HIV-coinfected patients: A systematic review and meta-analysis. Clinical Infectious Diseases 50(9), 1288-1299 (2010). 6.McIlleron, H.,Meintjes, G.,Burman, W.J., et al. Complications of antiretroviral therapy in patients with tuberculosis: Drug interactions, toxicity, and immune reconstitution inflammatory syndrome. Journal of Infectious Diseases 196, S63-S75 (2007). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 847 |
| 分子式 | C46H62N4O11 |
| CAS号 | 72559-06-9 |
| 稳定性 | ≥ 2 years |
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