4-Thiouridine
货号：
16373-5mg 基本售价：
406.0 元 规格：
5 mg
产品信息
概述| 货号 | 16373-5mg |
| 描述 | 4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling.1,2,3 The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU differs from uridine only by a single sulfur substitution. This offers the advantage of incorporating into an RNA chain with minimal structural perturbation and with similar base-pairing properties, reducing the likelihood that substitution will impair RNA interactions or activities.3 |
| 别名 | NSC 518132;4-SU; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Burger, K.,Mühl, B.,Kellner, M., et al. 4-Thiouridine inhibits rRNA synthesis and causes a nucleolar stress response. RNA Biol. 10(10), 1623-1630 (2013).
2.Thomas, G. and Favre, A. 4-Thiouridine triggers both growth delay induced by near-ultraviolet light and photoprotection. European Journal of Biochemistry 113(1), 67-74 (1980).
3.Harris, M.E. and Christian, E.L. RNA crosslinking methods. Methods in Enzymology 468, 127-146 (2009).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 260.3 |
| 分子式 | C9H12N2O5S |
| CAS号 | 13957-31-8 |
| 稳定性 | ≥ 2 years |
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