货号 | 16111-25mg |
描述 | 5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA as well as DNA for certain organisms.1,2 Roughly one to two residues of 5-methylcytidine occur in every 1,000 RNA residues.3 It has been used in epigenetics research, especially in studies involving DNA methylation processes involved in the establishment of genomic imprinting and in the control of gene expression and differentiation.4 |
别名 | NSC 363933; |
供应商 | Cayman |
应用文献 | |
1.Edelheit, S.,Schwartz, S.,Mumbach, M.R., et al. Transcriptome-wide mapping of 5-methylcytidine RNA modifications in bacteria, archaea, and yeast reveals m5C within archaeal mRNAs. PLoS Genetics 9(6), e1003602 (2013). 2.Mahto, S.K. and Chow, C.S. Probing the stabilizing effects of modified nucleotides in the bacterial decoding region of 16S ribosomal RNA. Bioorganic & Medicinal Chemistry 21(10), 2720-2726 (2013). 3.Guntaka, R.V.,Katz, R.A.,Weiner, A.J., et al. Effect of 5-methylcytidine on virus production in avian sarcoma virus-infected chicken embryo cells. Journal of Virology 29(2), 475-482 (1979). 4.Zhu, R.,Howorka, S.,Pröll, J., et al. Nanomechanical recognition measurements of individual DNA molecules reveal epigenetic methylation patterns. Nat.Nanotechnol. 5(11), 788-791 (2010). | |
运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 257.2 |
分子式 | C10H15N3O5 |
CAS号 | 2140-61-6 |
稳定性 | ≥ 2 years |
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