15(R),19(R)-hydroxy Prostaglandin F1α
货号：
15920-50ug 基本售价：
406.0 元 规格：
50 ug
产品信息
概述| 货号 | 15920-50ug |
| 描述 | 19(R)-Hydroxylated prostaglandins occur in µg/ml concentrations in the semen of certain mammalian species, especially primates. In the case of humans, the compounds are primarily of the PGE series, and the hydroxyl stereochemistry is 15(S),19(R).1 19(R)-Hydroxylated prostaglandins are also found in the seminal plasma of marsupials, where F-type compounds of the 1 and 2-series predominate.2 The 15(R)-hydroxy epimer of these 19-hydroxylated prostaglandins is the inverse or “unnatural” isomer at C-15. The biological role of 19(R)-hydroxylated prostaglandins is not well established. In the F-series, 19(R)-hydroxylation is associated with a significant loss of receptor-mediated biological activity in some assays.3 |
| 别名 | 15(R),19(R)-hydroxy PGF1α; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Cooper, I. and Kelly, R.W. The measurement of E and 19-hydroxy E prostaglandins in human seminal plasma. Prostaglandins 10, 507-514 (1975).
2.Marley, P.B.,Rodger, J.C.,White, I.G., et al. 19-Hydroxylated prostaglandins in the semen of the marsupial Trichosurus vulpecula (brush-tailed possum). Comparative Biochemistry and Physiology 70B, 619-621 (1981).
3.Woodward, D.F.,Protzman, C.E.,Krauss, A.H.P., et al. Identification of 19(R)-OH prostaglandin E2 as a selective prostanoid EP2-receptor agonist. Prostaglandins 46, 371-383 (1993).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 372.5 |
| 分子式 | C20H36O6 |
| 稳定性 | ≥ 1 year |
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