L-Glutathione, oxidized (sodium salt)
货号：
15491-100mg 基本售价：
406.0 元 规格：
100 mg
产品信息
概述| 货号 | 15491-100mg |
| 描述 | Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell.1 GSSG is the oxidized form of GSH (Item No. 10007461). It can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase.1 GSSG functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation post translational modifications.2 The ratio of reduced glutathione to oxidized glutathione within cells is often used as an indicator of oxidative stress, with higher concentrations of GSSG predicting increased oxidative stress.3 |
| 别名 | GSSG; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Pompella, A.,Visvikis, A.,Paolicchi, A., et al. The changing faces of glutathione, a cellular protagonist. Biochemical Pharmacology 66, 1499-1503 (2003).
2.Giustarini, D.,Rossi, R.,Milzani, A., et al. S-glutathionylation: From redox regulation of protein functions to human diseases. Journal of Cellular and Molecular Medicine 8(2), 201-212 (2004).
3.Schafer, F.Q. and Buettner, G.R. Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. Free Radical Biology & Medicine 30(11), 1191-1212 (2001).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 656.6 |
| 分子式 | C20H30N6O12S2 • 2Na |
| CAS号 | 103239-24-3 |
| 稳定性 | ≥ 2 years |
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