货号 | 15331-500ug |
描述 | Ginsenosides are pharmacologically active natural compounds from ginseng and other plants of the genus Panax.1 Structurally, they are steroid glycosides derived from the triterpene squalene.1 Ginsenoside Rg2 is a protopanaxatriol that is more abundant in some Panax species (e.g., white and red P. ginseng) than others.2 This ginsenoside and its metabolites have diverse in vitroandin vivo effects, including neuroprotective, anti-inflammatory, and anti-diabetic actions.3,4,5 It also protects against DNA damage and apoptosis induced by ultraviolet light.6 Notably, this ginsenoside is increased by the metabolism of other bioactive ginsenosides during the steaming or heating of plant materials, particularly in P. quinquefolium.2,7 |
别名 | Chikusetsusaponin I;Panaxoside Rg2;Prosapogenin C2; |
供应商 | Cayman |
应用文献 | |
1.Liang, Y. and Zhao, S. Progress in understanding of ginsenoside biosynthesis. Plant Biol.(Stuttg) 10(4), 415-421 (2008). 2.Chen, C.F.,Chiou, W.F. and Zhang, J.T. Comparison of the pharmacological effects of Panax ginseng and Panax quinquefolium. Acta.Pharmacol.Sin. 29(9), 1103-1108 (2008). 3.Zhang, G.,Liu, A.,Zhou, Y., et al. Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia. Journal of Ethnopharmacology 115(3), 441-448 (2008). 4.Cho, Y.S.,Kim, C.H.,Ha, T.S., et al. Ginsenoside Rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell. Korean J.Physiol.Pharmacol. 17(2), 133-137 (2013). 5.Yuan, H.D.,Kim, D.Y.,Quan, H.Y., et al. Ginsenoside Rg2 induces orphan nuclear receptor SHP gene expression and inactivates GSK3β via AMP-activated protein kinase to inhibit hepatic glucose production in HepG2 cells. Chemico-Biological Interactions 195(1), 35-42 (2012). 6.Ha, S.E.,Shin, D.H.,Kim, H.D., et al. Effects of ginsenoside Rg2 on the ultraviolet B-induced DNA damage responses in HaCaT cells. Naunyn-Schmiedebergs Archives of Pharmacology 382(1), 89-101 (2010). 7.Kim, I.W.,Cha, K.M.,Wee, J.J., et al. A new validated analytical method for the quality control of red ginseng products. J.Ginseng Res. 37(4), 475-482 (2013). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 785 |
分子式 | C42H72O13 |
CAS号 | 52286-74-5 |
稳定性 | ≥ 2 years |
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