ML-180
货号：
15181-1mg 基本售价：
406.0 元 规格：
1 mg
产品信息
概述| 货号 | 15181-1mg |
| 描述 | ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC50 = 3.7 µM) with maximum efficacy of 64% repression.1 It is inactive at the related steroidogenic factor-1 transcriptional activator.1 Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the death of estrogen-receptor negative MDA-MB-231 breast cancer cells, and inhibits the steroidogenic acute regulatory promoter (IC50 = 2.05 µM).1 |
| 别名 | CID-3238389;SR1848; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Busby, S.,Nuhant, P.,Cameron, M., et al. Discovery of inverse agonists for the liver receptor homologue-1 (LRH1; NR5A2). 1-55 (2010).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 388.9 |
| 分子式 | C20H25ClN4O2 |
| CAS号 | 863588-32-3 |
| 稳定性 | ≥ 2 years |
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