Riluzole (hydrochloride)
货号：
14577-10mg 基本售价：
406.0 元 规格：
10 mg
产品信息
概述| 货号 | 14577-10mg |
| 描述 | Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 μM).1 Riluzole suppresses glutamate-induced seizures in rats at an ED50 value of 3.2 mg/kg and displays neuroprotective effects in hypoxic animals at an ED50 value of 4 mg/kg.1 Riluzole has been explored as a therapeutic for slowing disease progression of amyotrophic lateral sclerosis.1 |
| 别名 | PK 26124; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Cheah, B.C.,Vucic, S.,Krishnan, A.V., et al. Riluzole, neuroprotection and amyotrophic lateral sclerosis. Current Medicinal Chemistry 17(18), 1942-1959 (2010).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥99% |
| 计算分子量 | 270.7 |
| 分子式 | C8H5F3N2OS • HCl |
| CAS号 | 850608-87-6 |
| 稳定性 | ≥ 6 months |
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