| 货号 | 14499-10mg |
| 描述 | Blasticidin S is a peptidyl nucleoside antibiotic. It was first isolated from S. griseochromogenes.1 The structure of the pentahydrate form was determined using diffractometer data and, similar to the antibiotic amicetin, the hydrophilic and hydrophobic groups lie on either side of the molecule.2 It has since been created using total synthesis.3 Blasticidin S (hydrochloride) is used in research to select mammalian cells transfected with the blasticidin resistance gene bsr.4 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Takeuchi, S.,Hirayama, K.,Ueda, K., et al. Blasticidin S, a new antibiotic. J. Antibiot. (Tokyo) 11(1), 1-5 (1958). 2.Swaminathan, V.,Smith, J.L.,Sundaralingam, M., et al. Crystal and molecular structure of the antibiotic blasticidin S hydrochloride pentahydrate. Biochim Biophys. Acta. 655(3), 335-341 (1981). 3.Ichikawa, Y.,Hirata, K.,Ohbayashi, M., et al. Total synthesis of (+)-blasticidin s. Chemistry 10(13), 3241-3251 (2004). 4.Izumi, M.,Miyaza, H.,Kamakura, T., et al. Blasticidin S-resistance gene (bsr): A novel selectable marker for mammalian cells. Exp. Cell Res. 197(2), 229-233 (1991). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 458.9 |
| 分子式 | C17H26N8O5 • HCl |
| CAS号 | 589205 |
| 稳定性 | ≥ 2 years |
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