| 货号 | 14332-50mg |
| 描述 | Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the gastrointestinal tract.1,2,3,4 Serotonin is important in the regulation of mood, sleep, vomiting, sexuality, and appetite. Low levels of serotonin are associated with several disorders, including depression, migraines, bipolar disorder, and anxiety. Its actions are terminated primarily via uptake of serotonin from the synapse. Serotonin reuptake can be inhibited with MDMA, cocaine, tricyclic antidepressants, and selective serotonin reuptake inhibitors. |
| 别名 | 5-HT;5-Hydroxytryptamine; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Martinez, A.,Knappskog, P.M. and Haavik, J. A structural approach into human tryptophan hydroxylase and its implications for the regulation of serotonin biosyntheis. Current Medicinal Chemistry 8, 1077-1091 (2001). 2.Liu, Q.,Yang, Q.,Sun, W., et al. Discovery and characterization of novel tryptophan hydroxylase inhibitors that selectively inhibit serotonin synthesis in the gastrointestinal tract. Journal of Pharmacology and Experimental Therapeutics 325, 47-55 (2008). 3.Schmid, C.L. and Bohn, L.M. Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a β-arrestin2/Src/Akt signaling complex in vivo. Journal of Neuroscience 30(40), 13513-13524 (2010). 4.Berger, M.,Gray, J.A. and Roth, B.L. The expanded biology of serotonin. Annual Reviews of Medicine 60, 355-366 (2009). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 212.7 |
| 分子式 | C10H12N2O • HCl |
| CAS号 | 153-98-0 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |