Valilactone
货号：
13690-500ug 基本售价：
406.0 元 规格：
500 ug
产品信息
概述| 货号 | 13690-500ug |
| 描述 | Valilactone is an esterase inhibitor produced by a cultured strain of soil actinomycetes.1 It is reported to inhibit hog liver esterase and hog pancreas lipase with IC50 values of 29 and 0.14 ng/ml, respectively.1 Valilactone can also inhibit fatty acid synthase with an IC50 value of 0.30 µM and demonstrates selective toxicity towards MDA-MB-231 breast cancer cells with an IC50 value of 10.5 µM.2 |
| 别名 | (-)-Valilactone; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kitahara, M.,Asano, M.,Naganawa, H., et al. Valilactone, an inhibitor of esterase, produced by actinomycetes. J. Antibiot. (Tokyo) 40(11), 1647-1650 (1987).
2.Richardson, R.D.,Ma, G.,Oyola, Y., et al. Synthesis of novel β-lactone inhibitors of fatty acid synthase. Journal of Medicinal Chemistry 51, 5285-5296 (2008).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 397.6 |
| 分子式 | C22H39NO5 |
| CAS号 | 113276-96-3 |
| 稳定性 | ≥ 2 years |
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