MPI-0441138
货号：
13098-1mg 基本售价：
406.0 元 规格：
1 mg
产品信息
概述| 货号 | 13098-1mg |
| 描述 | MPI-0441138 is a potent inducer of apoptosis and growth inhibition (EC50 = 2 nM for both processes, based on caspase-3 activation and total cellular ATP, respectively) in T47D and HCT116 cells.1,2 MPI-0441138 has excellent blood brain barrier penetration and is effective in mouse xenograft cancer models.1,2 |
| 别名 | EP128265; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sirisoma, N.,Kasibhatla, S.,Pervin, A., et al. Discovery of 2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine (EP128265, MPI-0441138) as a potent inducer of apoptosis with high in vivo activity. Journal of Medicinal Chemistry 51, 4771-4779 (2008).
2.Sirisoma, N.,Pervin, A.,Zhang, H., et al. Discovery of N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a potent apoptosis inducer and efficacious anticancer agent with high blood brain barrier penetration. J. Med. Chem. 52(8), 2341-2351 (2009).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 299.8 |
| 分子式 | C16H14ClN3O |
| CAS号 | 827030-33-1 |
| 稳定性 | ≥ 2 years |
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