Citreoviridin
货号：
11319-500ug 基本售价：
406.0 元 规格：
500 ug
产品信息
概述| 货号 | 11319-500ug |
| 描述 | Citreoviridin is a mycotoxin isolated from several Penicillium species that has been shown to inhibit the mitochondrial ATP synthetase system.1,2 It inhibits soluble ATPase (KD = 4.1 µM), ADP-stimulated respiration in isolated rat liver mitochondria (KD = 0.15 µM), and ATP-driven reduction of NAD+ by succinate (KD = 2 µM).1 Citreoviridin has been used to target ectopic ATPase activity in cancer cells in order to modulate the metabolic activity associated with tumorigenesis.3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Linnett, P.E.,Mitchell, A.D.,Osselton, M.D., et al. Citreoviridin, a specific inhibitor of the mitochondiral adenosine triphosphatase. Biochemistry Journal 170(3), 503-510 (1978).
2.Gause, E.M.,Buck, M.A., and Douglas, M.G. Binding of citreoviridin to the β subunit of the yeast F1-ATPase. The Journal of Biological Chemisty 256(2), 557-559 (1981).
3.Wu, Y.H.,Hu, C.W.,Chien, C.W., et al. Quantitative proteomic analysis of human lung tumor xenografts treated with the ectopic ATP synthase inhibitor citreoviridin. PLoS One 8(8), 1-19 (2013).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 402.5 |
| 分子式 | C23H30O6 |
| CAS号 | 25425-12-1 |
| 稳定性 | ≥ 2 years |
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