HZ52
货号：
10888-1mg 基本售价：
406.0 元 规格：
1 mg
产品信息
概述| 货号 | 10888-1mg |
| 描述 | HZ-52 is a potent, reversible inhibitor of 5-lipoxygenase, blocking leukotriene synthesis with an IC50 value of 0.7 μM in intact human polymorphonuclear leukocytes.1 HZ-52 also attenuates leukotriene B4 synthesis, prevents carrageenan-induced pleurisy, and protects against platelet-activating factor-induced shock in mice when given intraperitoneally (10 mg/kg).1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Greiner, C.,Hörnig, C.,Rossi, A., et al. 2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidin-2-ylthio)octanoic acid (HZ52) - a novel type 5-lipoxygenase inhibitor with favorable molecular pharmacology and efficacy in vivo. British Journal of Pharmacology 164(2b), 781-793 (2011).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 456 |
| 分子式 | C24H26ClN3O2S |
| CAS号 | 1077626-51-7 |
| 稳定性 | ≥ 2 years |
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