CAY10568
货号：
10012565-10mg 基本售价：
406.0 元 规格：
10 mg
产品信息
概述| 货号 | 10012565-10mg |
| 描述 | Most local anesthetics act by abolishing voltage gated sodium channel currents indiscriminately in all populations of neurons. Selective analgesia through TRPV1-mediated entry of a cationic lidocaine derivative, QX314, was recently reported.1 CAY10568 is a physically smaller, less hydrophobic version of QX314 designed to be even more permeable to TRPV1 ion channel when activated by agonists such as capsaicin and N-oleoyl dopamine. CAY10568 when given in combination with suitable TRPV1 agonists should produce selective blockade of the pain response while leaving motor, touch, and proprioception intact. |
| 别名 | Santinamide; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Binshtok, A.M.,Bean, B.P., and Woolf, C.J. Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers. Nature 449, 607-610 (2007).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 320.2 |
| 分子式 | C11H17N2O ?I |
| CAS号 | 22913-17-3 |
| 稳定性 | ≥ 2 years |
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