β-Gal-NONOate
货号:
10009137-1mg 基本售价:
406.0 元 规格:
1 mg
产品信息
概述货号 | 10009137-1mg |
描述 | β-Gal-NONOate is a nitric oxide (NO) donor which releases NO following activation by β-galactosidase.1 β-Gal-NONOate is stabile in aqueous solution at neutral and acidic pH for several hours, exhibits good water solubility, and is able to cross the cell membrane. Following enzymatic hydrolysis, β-Gal-NONOate decomposes with a half-life of six minutes at pH 5.6.1 β-Gal-NONOate is cytotoxic to a number of cancer cell-lines and exhibits high bactericidal activity against E. coli transformed with the β-galactosidase gene.1,2 |
性能供应商 | Cayman |
应用文献 |
1.Wu, X.,Tang, X.,Xian, M., et al. Glycosylated diazeniumdiolates: a novel class of enzyme-activated nitric oxide donors. Tetrahedron Letters 42, 3779-3782 (2001). 2.Chen, C.,Shi, Y.Q.,Song, J., et al. Delivery of nitric oxide released from β-Gal-NONOate activation by β-galactosidase and its activity against Escherichia coli. Biological and Pharmaceutical Bullentin 29(6), 1239-1241 (2006).
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运输条件 | Dry ice in continental US; may vary elsewhere |
存放说明 | -80 |
纯度 | ≥98% |
计算分子量 | 293.3 |
分子式 | C10H19N3O7 |
CAS号 | 357192-77-9 |
稳定性 | ≥ 1 year |
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