PI-3065
货号：
9002394-1mg 基本售价：
392.0 元 规格：
1 mg
产品信息
概述| 货号 | 9002394-1mg |
| 描述 | PI-3065 is a potent inhibitor of phosphatidylinositol 3-kinase (PI3K) isoform p110δ (IC50 = 15 nM).1 It displays greater than 100-fold selectivity for p110δ over p110ɑ, p110β, p110γ, DNA-PK, or mTOR.1 PI-3065 suppresses tumor growth and metastasis in mouse xenograft models by inhibiting p110δ activity in regulatory T cells.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ali, K.,Soond, D.R.,Pineiro, R., et al. Inactivation of PI3K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer. Nature 510(7505), 407-411 (2014).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 506.6 |
| 分子式 | C27H31FN6OS |
| CAS号 | 955977-50-1 |
| 稳定性 | ≥ 2 years |
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