Azelastine (hydrochloride)
货号：
20873-5mg 基本售价：
392.0 元 规格：
5 mg
产品信息
概述| 货号 | 20873-5mg |
| 描述 | Azelastine is a second generation antihistamine that targets the histamine H1 receptor (Ki = 6.4 nM).1,2 It displays a terminal half-life of 25 hours in man.2 Azelastine may be combined with the synthetic glucocorticoid fluticasone in certain formulations for the improvement of symptoms related to allergies.3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kubo, N.,Shirakawa, S.,Kuno, T., et al. Antimuscarinic effects of antihistamines: Quantitative evaluation by receptor-binding assay. Japanese Journal of Pharmacology 43(3), 277-282 (1987).
2.Tillement, J.P. The advantages for an H1 antihistamine of a low volume of distribution. Allergy 55(suppl 60), 17-21 (2000).
3.Prenner, B.M. A review of the clinical efficacy and safety of MP-AzeFlu, a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate, in clinical studies conducted during different allergy seasons in the US. J. Asthma Allergy 9, 135-143 (2016).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 418.4 |
| 分子式 | C22H24ClN3O • HCl |
| CAS号 | 79307-93-0 |
| 稳定性 | ≥ 2 years |
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