RGD Peptide
货号：
14501-1mg 基本售价：
392.0 元 规格：
1 mg
产品信息
概述| 货号 | 14501-1mg |
| 描述 | RGD peptide is a synthetic compound made up of the arginine-glycine-aspartate motif that has been extensively used to inhibit integrin-ligand interactions in studies related to cell adhesion, migration, growth, and differentiation.1 RGD peptide has also been shown to directly induce apoptosis, independent of integrin-mediated cell clustering or signals, by initiating conformational changes that enhance pro-caspase-3 activation and autoprocessing.2,3 |
| 别名 | GRGDNP;H-Gly-Arg-Gly-Asp-Asn-Pro-OH; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ruoslahti, E. and Öbrink, B. Common principles in cell adhesion. Experimental Cell Research 227, 1-11 (1996).
2.Buckley, C.D.,Pilling, D.,Henriquez, N.V., et al. RGD peptides induce apoptosis by direct caspase-3 activation. Nature 397, 534-539 (1999).
3.Adderley, S.R. and Fitzgerald, D.J. Glycoprotein IIb/IIIa antagonists induce apoptosis in rat cardiomyocytes by caspase-3 activation. The Journal of Biological Chemisty 275, 5760-5766 (2000).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 614.6 |
| 分子式 | C23H38N10O10 |
| CAS号 | 114681-65-1 |
| 稳定性 | ≥ 2 years |
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