Citrinin
货号：
11320-1mg 基本售价：
392.0 元 规格：
1 mg
产品信息
概述| 货号 | 11320-1mg |
| 描述 | Citrinin is a mycotoxin originally isolated from P. citrinum that is also produced by a variety of other fungi that are found as contaminants in human foodstuffs and animal feeds.1 Citrinin exerts cytotoxic and genotoxic effects in various mammalian cells, causing mycotoxic nephropathy in livestock and Balkan nephropathy and yellow rice fever in humans.1 Because citrinin induces apoptosis and blocks tubulin polymerization as well as mitotic spindle assembly, it is useful as a biological research reagent.2,3 |
| 别名 | NSC 186; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Bennett, J.W., and Klich, M. Mycotoxins. Clin.Microbiol.Rev. 16(3), 497-516 (2003).
2.Chan, W.H. Citrinin induces apoptosis via a mitochondria-dependent pathway and inhibition of survival signals in embryonic stem cells, and causes developmental injury in blastocysts. Biochemistry Journal 404, 317-326 (2007).
3.Chang, C.H.,Yu, F.Y.,Wu, T.S., et al. Mycotoxin citrinin induced cell cycle G2/M arrest and numerical chromosomal aberration associated with disruption of microtubule formation in human cells. Toxicological Sciences 119(1), 84-92 (2011).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 250.3 |
| 分子式 | C13H14O5 |
| CAS号 | 518-75-2 |
| 稳定性 | ≥ 2 years |
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