Arvanil
货号：
90052-5mg 基本售价：
378.0 元 规格：
5 mg
产品信息
概述| 货号 | 90052-5mg |
| 描述 | Arvanil is a structural analog of capsaicin, which is the noxious active component of hot peppers of the Capsicum family. It is the amide of vanillylamine and arachidonic acid. Arvanil induces analgesia in rat and mouse models of pain.1 Arvanil has complex interactions with the cannabinoid system, in that it potentiates the agonist activity of endogenous cannabinoids by inhibiting the reuptake of arachidonoyl ethanolamide (AEA). It is an agonist at CB1(Ki values of 0.25 to 0.52 μM), but not CB2, receptors, and is resistant to hydrolysis by FAAH.2 The vasodilator, analgesic, and anti-inflammatory properties of arvanil are not clearly explained by its interactions with cannabinoid and vanilloid receptors, suggesting other possible sites of action. |
| 别名 | N-Vanillylarachidonamide; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Janusz, J.M.,Buckwalter, B.L.,Young, P.A., et al. Vanilloids. 1. Analogs of capsaicin with antinociceptive and antiinflammatory activity. Journal of Medicinal Chemistry 36, 2595-2604 (1993).
2.Di Marzo, V.,Bisogno, T.,Melck, D., et al. Interactions between synthetic vanilloids and the endogenous cannabinoid system. FEBS Letters 436, 449-454 (1998).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 439.6 |
| 分子式 | C28H41NO3 |
| CAS号 | 128007-31-8 |
| 稳定性 | ≥ 1 year |
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