SIN-1 (chloride)
货号:
82220-10mg 基本售价:
378.0 元 规格:
10 mg
产品信息
概述货号 | 82220-10mg |
描述 | As the active metabolite of molsidomine, SIN-1 (chloride) is a potent vasorelaxant and inhibitor of platelet aggregation. It produces both NO and superoxide and can therefore be used to generate peroxynitrite under physiological conditions.1,2,3 |
别名 | Linsidomine;3-Morpholino-sydnonimine; |
性能供应商 | Cayman |
应用文献 |
1.Rosenkranz, B.,Winkelmann, B.R., and Parnham, M.J. Clinical pharmacokinetics of molsidomine. Clinical Pharmacokinetics 30, 372-384 (1996). 2.Lomonosova, E.E.,Kirsch, M.,Rauen, U., et al. The critical role of hepes in SIN-1 cytotoxicity, peroxynitrite versus hydrogen peroxide. Free Radical Biology & Medicine 24, 522-528 (1998). 3.Nishikawa, M.,Kanamori, M., and Hidaka, H. Inhibition of platelet aggregation and stimulation of guanylate cyclase by an antianginal agent molsidomine and its metabolites. Journal of Pharmacology and Experimental Therapeutics 220, 183-190 (1982).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥99% |
计算分子量 | 206.6 |
分子式 | C6H11N4O2 • Cl |
CAS号 | 16142-27-1 |
稳定性 | ≥ 2 years |
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