Azelaoyl PAF
货号：
60924-500ug 基本售价：
378.0 元 规格：
500 ug
产品信息
概述| 货号 | 60924-500ug |
| 描述 | Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ.1 One of these substances was recently isolated and purified from oxLDL, and identified as azelaoyl PAF.2 Azelaoyl PAF is a potent PPARγ agonist which competes for the thiazolidinedione binding site. Azelaoyl PAF is more potent than 15-deoxy-Δ12,14-prostaglandin J2, and equipotent with rosiglitazone as a ligand for this receptor.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Tontonoz, P.,Nagy, L.,Alvarez, J.G.A., et al. PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 93, 241-252 (1998).
2.Davies, S.S.,Pontsler, A.V.,Marathe, G.K., et al. Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor γ ligands and agonists. The Journal of Biological Chemisty 276, 16015-16023 (2001).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 651.9 |
| 分子式 | C33H66NO9P |
| CAS号 | 354583-69-0 |
| 稳定性 | ≥ 1 year |
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