Tinidazole
货号:
21755-10g 基本售价:
378.0 元 规格:
10 g
产品信息
概述货号 | 21755-10g |
描述 | Tinidazole is a 5-nitroimidazole derivative with antiparasitic and antibiotic activity that exhibits a mean minimum inhibitory concentration of 0.31, 2.33, and 0.5 μg/mL against C. difficile,P. bivia, and B. fragilis, respectively.1,2 It is orally bioavailable and is rapidly metabolized to cytotoxic intermediates that covalently bind DNA, causing irreversible damage to susceptible cells.1,2 It shows efficacy against pathogenic protozoa (T. vaginalis,E. bistolytica, and G. duodenalis), clinically significant anaerobic bacteria (B. fragilis,C. difficile), and microaerophilic bacterium (H. pylori).2 |
别名 | CP 12,574; |
性能供应商 | Cayman |
应用文献 |
1.Citron, D.M.,Tyrrell, K.L.,Warren, Y.A., et al. In vitro activities of tinidazole and metronidazole against Clostridium difficile, Prevotella bivia and Bacteroides fragilis. Anaerobe 11(6), 315-317 (2005). 2.Fung, H.B., and Doan, T.L. Tinidazole: A nitroimidazole antiprotozoal agent. Clin. Ther. 27(12), 1859-1884 (2005).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 247.3 |
分子式 | C8H13N3O4S |
CAS号 | 19387-91-8 |
稳定性 | ≥ 2 years |
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