Arachidonic Acid ethyl ester
货号：
10008200-25mg 基本售价：
378.0 元 规格：
25 mg
产品信息
概述| 货号 | 10008200-25mg |
| 描述 | Arachidonic acid is the keystone essential fatty acid at the origin of the arachidonic acid cascade. It is converted by cyclooxygenase, lipoxygenase, and epoxygenase enzymes into more than one hundred fifty different potent primary autacoid metabolites in species ranging from fungi to plants to mammals. Arachidonic acid is stored in tissue phospholipids in esterified form, where it comprises a small but critically controlled percentage of the polyunsaturated fatty acid pool.1 Arachidonic acid ethyl ester is a more lipophilic form of arachidonic acid that can be incorporated into dietary regimens or fed to cultured cells as a source of exogenous arachidonate. It is one of the fatty acid ethyl esters that increase cytosolic Ca2+ concentration leading to pancreatic acinar cell injury due to excessive consumption of ethanol.2 Whereas arachidonic acid inhibits dopamine uptake, the ethyl esterified version does not retain this property.3 |
| 别名 | Ethyl Arachidonate; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Holman, R.T. Control of polyunsaturated acids in tissue lipids. Journal of the American College of Cardiology 5, 183-211 (1986).
2.Chen, N.,Appell, M.,Berfield, J.L., et al. Inhibition by arachidonic acid and other fatty acids of dopamine uptake at the human dopamine transporter. European Journal of Pharmacology 478, 89-95 (2003).
3.Criddle, D.N.,Raraty, M.G.T.,Neoptolemos, J.P., et al. Ethanol toxicity in pancreatic acinar cells: Mediation by nonoxidative fatty acid metabolites. Proceedings of the National Academy of Sciences of the United States of America 101(29), 10738-10743 (2004).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | >98% |
| 计算分子量 | 332.5 |
| 分子式 | C22H36O2 |
| CAS号 | 1808-26-0 |
| 稳定性 | ≥ 1 year |
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