TRIM
货号：
81310-50mg 基本售价：
364.0 元 规格：
50 mg
产品信息
概述| 货号 | 81310-50mg |
| 描述 | TRIM is an inhibitor of nNOS and iNOS. It exhibits IC50 values of 28.2 µM, 27.0 µM, and 1.06 mM for the inhibition of nNOS (mouse), iNOS (rat), and eNOS (bovine), respectively.1 TRIM inhibits mouse nNOS with Ki values of 47.3 and 462 µM in the absence and presence of BH4, respectively, suggesting TRIM interferes with both arginine and tetrahydrobiopterin binding.2 |
| 别名 | 1-(α,α,α-trifluoro-o-tolyl)-Imidazole; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Handy, R.L.C.,Wallace, P.,Gaffen, Z.A., et al. The antinociceptive effect of 1-(2-trifluoromethylphenyl) imidazole (TRIM), a potent inhibitor of neuronal nitric oxide synthase in vitro, in the mouse. British Journal of Pharmacology 116, 2349-2350 (1995).
2.Handy, R.L.C., and Moore, P.K. Mechanism of the inhibition of neuronal nitric oxide synthase by 1-(2-trifluoromethylphenyl) imidazole (TRIM). Life Sciences 60, 389-394 (1997).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 212.2 |
| 分子式 | C10H7N2F3 |
| CAS号 | 25371-96-4 |
| 稳定性 | ≥ 1 year |
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