BRD7389
货号：
20214-1mg 基本售价：
364.0 元 规格：
1 mg
产品信息
概述| 货号 | 20214-1mg |
| 描述 | BRD7389 is an inhibitor of ribosomal S6 kinases (RSKs; IC50s = 1.5, 2.4, and 1.2 μM for RSK1, RSK2, and RSK3, respectively).1 Through this action, BRD7389 causes mouse αTC1 pancreatic α cells to adopt several morphological and gene expression features of β cells, including increased insulin expression.1 BRD7389 also enhances glucose-stimulated insulin and glucagon secretion by pancreatic islet cells isolated from human donors with a low body mass index.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Fomina-Yadlin, D.,Kubicek, S.,Walpita, D., et al. Small-molecule inducers of insulin expression in pancreatic α-cells. Proc. Natl. Acad. Sci. USA 107(34), 15099-15104 (2010).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 366.4 |
| 分子式 | C24H18N2O2 |
| CAS号 | 376382-11-5 |
| 稳定性 | ≥ 2 years |
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