Miconazole (nitrate)
货号：
15420-1g 基本售价：
364.0 元 规格：
1 g
产品信息
概述| 货号 | 15420-1g |
| 描述 | Miconazole is a widely used antifungal imidazole that acts by inhibiting the 14α-demethylation of lanosterol, which consequently leads to the inhibition of ergosterol synthesis in fungal cell membranes.1,2 Additionally, miconazole has been shown to induce reactive oxygen species in fungal biofilms, demonstrating a MIC value of ≥256 μM against Candidaspp.3 |
| 别名 | NSC 169434;R 14889; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Vanden Bossche, H.,Marichal, P.,Gorrens, J., et al. Biochemical approaches to selective antifungal activity. Focus on azole antifungals. Mycoses 32(Suppl 1), 35-52 (1989).
2.Saag, M.S. and Dismukes, W.E. Azole antifungal agents: Emphasis on new triazoles. Antimicrobial Agents and Chemotherapy 32(1), 1-8 (1988).
3.Delattin, N.,Cammue, B.P.A. and Thevissen, K. Reactive oxygen species-inducing antifungal agents and their activity against fungal biofilms. Future Med.Chem. 6(1), 77-90 (2014).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 479.1 |
| 分子式 | C18H14Cl4N2O • HNO3 |
| CAS号 | 22832-87-7 |
| 稳定性 | ≥ 2 years |
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