Myoseverin
货号：
14642-1mg 基本售价：
364.0 元 规格：
1 mg
产品信息
概述| 货号 | 14642-1mg |
| 描述 | Myoseverin is a trisubstituted purine which binds microtubules, reversibly altering cellular function.1,2 At 20 μM, it directly binds tubulin and disrupts the structure of the microtubule cytoskeleton, resulting in myotube fission.1 Myoseverin arrests cell cycle in the G2/M phase, followed by DNA synthesis and cell proliferation after removal of the compound.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Rosania, G.R.,Chang, Y.T.,Perez, O., et al. Myoseverin, a microtubule-binding molecule with novel cellular effects. Nat.Biotechnol. 18(3), 304-308 (2000).
2.Moon, H.S.,Jacobson, E.M.,Khersonsky, S.M., et al. A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening. Journal of the American Chemical Society 124(39), 11608-11609 (2002).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 432.5 |
| 分子式 | C24H28N6O2 |
| CAS号 | 267402-71-1 |
| 稳定性 | ≥ 2 years |
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